100 Minutes with ILS

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Tune in and listen at “100 min with ILS” to our hot science frontiers topics covering all areas of lipidomics.

Connection details:

https://uni-regensburg.zoom.us/j/61901764412?pwd=TXlLcGlkK2xtQ0pSeENFWHFjYnlBdz09

 

Meeting ID: 619 0176 4412
Passcode: 137579

Sessions will be recorded. Recordings will be made accessible to ILS members below. Please log in to access.

If you would like to learn more about lipids in a series of tutorials, check out our “We Love Lipids” series.

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Connection Details: https://uni-regensburg.zoom.us/j/61901764412?pwd=TXlLcGlkK2xtQ0pSeENFWHFjYnlBdz09 Meeting ID: 619 0176 4412 Passcode: 137579

Next Event:

May 13th 2022 Organelle Lipidomics
Organelle Lipidomics

14 - 15 CEST, 8 - 9 EST

Markus A Keller, Biochemical Genetics, Medical Faculty Innsbruck

Metabolic coupling of cellular phospholipid pools controls mitochondrial cardiolipin diversity

Dr. Markus Keller is a trained Chemist and started studying lipid metabolism in the context of biomedical research during his PhD. The focus of his scientific work lies in the enzymology and properties of the lipid metabolic network. He applies LC-MS/MS based approaches and bioinformatic strategies to elucidate the regulation of lipid metabolism in the context of inborn errors of lipid metabolism.

Cristina Coman, Institute of Analytical Chemistry, University of Vienna, Austria

A Synaptoneurolipidomics View on Neuronal Plasticity

Dr. Cristina Coman received her BSc and MSc in Chemistry from the Babes-Bolyai University, in Romania. She finished her PhD in 2019 at the Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V., in Germany and is currently a postdoc at the Institute of Analytical Chemistry, University of Vienna. Her interests focus on developing and implementing lipid-centered multiomics strategies to increase the understanding of synapse related metabolism and processes.

Hosts: Robert Ahrends

August 26th 2022 Bioinfo Lipidomics
Bioinformatics Application in Lipidomics

14 - 15 CEST, 8 - 9 EST

Hosts: Nils Hoffmann & Robert Ahrends

September 30th 2022 Cardiolipidomics
Cardiolipidomics

14 - 15 CEST, 8 - 9 EST

Hosts: Markus Wenk

December 16th 2022 Structural Lipidomics
Structural Lipidomics

14 - 15 CET, 8 - 9 EST

Hosts: Yu Xia

Organell Lipidomics

May 13th, 2022 – 14:00 CEST, 8:00 am EST
Markus A Keller, Biochemical Genetics, Medical Faculty Innsbruck

Title: Metabolic coupling of cellular phospholipid pools controls mitochondrial cardiolipin diversity

Dr. Markus Keller is a trained Chemist and started studying lipid metabolism in the context of biomedical research during his PhD. The focus of his scientific work lies in the enzymology and properties of the lipid metabolic network. He applies LC-MS/MS based approaches and bioinformatic strategies to elucidate the regulation of lipid metabolism in the context of inborn errors of lipid metabolism.

Cristina Coman
Cristina Coman, Institute of Analytical Chemistry, University of Vienna, Austria

Title: A Synaptoneurolipidomics View on Neuronal Plasticity

Dr. Cristina Coman received her BSc and MSc in Chemistry from the Babes-Bolyai University, in Romania. She finished her PhD in 2019 at the Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V., in Germany and is currently a postdoc at the Institute of Analytical Chemistry, University of Vienna. Her interests focus on developing and implementing lipid-centered multiomics strategies to increase the understanding of synapse related metabolism and processes.

Past Events:

January 27th, 2022 New Year with New Lipids
Welcoming the New Year with New Lipids​

14 - 15 CET, 8 - 9 EST

Welcoming the New Year with New Lipids

Pieter C. Dorrestein, University of California at San Diego, California, U.S.A.

Isomeric lipid separations to assess membrane fluidity in antibiotic-resistant bacteria

Kelly Hines, University of Georgia, Athens, Georgia, U.S.A.

High throughput enzymatic assay for determining sn- selectivity of lysophosphatidylcholine acyltransferase

Xue Zhao, Tsinghua University, Beijing, China

Hosts: Erin Baker

April 8th 2022​ Beyond Good Lipidomic Practice​
Beyond Good Lipidomics Practice

14 - 15 CEST, 8 - 9 EST

Beyond Good Lipidomic Practice - Quality control in Lipidomics

Harald Köfeler, Core Facility for Mass Spectrometry and Lipidomics, Medical University of Graz, Austria

Reporting checklist for lipidomics – First glimpse of the online reporting system for evaluation of data quality

Dominik Kopczynski, Robert Ahrends, Institute of Analytical Chemistry, University of Vienna, Austria

Gerhard Liebisch, Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Germany

Hosts: Harald Köfeler

Beyond Good Lipidomic Practice

April 8th, 2022 – 16:00 CEST, 10:00 am EST
Köfeler
Harald Köfeler, Core Facility for Mass Spectrometry and Lipidomics, Medical University of Graz, Austria

Title: Beyond Good Lipidomic Practice – Quality control in Lipidomics

Harald Köfeler has actively worked in the field of Lipidomics for more than two decades. After his post-doctoral stay in in the lab of Michael L. Gross at Washington University, St. Louis, MO he returned to Graz, Austria where he is since 2004 running the Core Facility for Mass Spectrometry at the Medical University of Graz with particular emphasis on lipidomics. His research focus is on the development of mass spectrometric methods for lipidomics and on the development of lipidomics processing software, where he is one of the co-developers of Lipid Data Analyzer (LDA).

 

 

 

 

Title: Reporting checklist for lipidomics – First glimpse of the online reporting system for evaluation of data quality
Dominik Kopczynski, Robert Ahrends, Institute of Analytical Chemistry, University of Vienna, Austria

Prof. Dr. Robert Ahrends studied biochemistry in Gießen and did his doctorate at the Institute for Analytical Chemistry at the Humboldt University in Berlin. He then went to Agilent Technologies for a year to develop analytical measurement methods before moving to Stanford University (Chemical and Systems Biology), USA as a postdoc. In 2013 he returned to Germany as a group leader at the Leibniz Institute for Analytical Sciences (ISAS) in Dortmund. Since January 2020 he has been working as Prof. at the Faculty of Chemistry, University of Vienna.

With his group, Ahrends combines state-of-the-art mass spectrometry and data analysis methods (https://lifs-tools.org/) for the global elucidation of lipidomes. His main focus here is on cardiovascular lipid metabolism and signal transduction, in which he develops very sensitive analysis methods for lipids and their corresponding proteins for specific questions https://lipidomics.at/.

 
Gerhard Liebisch, Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Regensburg, Germany

PD Dr. Gerhard Liebisch obtained his Ph.D. at the University of Regensburg. He is a research associate at the Institute of Clinical Chemistry and Laboratory Medicine at the University Hospital of Regensburg and is responsible for the instrumental analytics lab (https://lipidomics-regensburg.de/).

His research interests focus on the development of mass spectrometric methods for the quantification of lipid species. For more than 20 years, these methods have been applied in large-scale clinical studies and basic research including the use of stable isotope-labeled lipid(s)/-precursor to trace the transport and metabolism of lipids. He is a co-founder of the Lipidomics Standards Initiative and a board member of the International Lipidomics Society.

 

 

Welcoming the New Year with New Lipids

January 27th, 2022 – 16:00 CET, 10:00 am EST
Pieter C. Dorrestein, University of California at San Diego, California, U.S.A.

Title: Welcoming the New Year with New Lipids

Pieter Dorrestein uses mass spectrometry to eavesdrop on the molecular conversations between microbes and their world. To produce the image, researchers swabbed every surface in the room, including the people, several hundred times, then analyzed the swabs with mass spectrometry to identify the chemicals present.

Our work aims to develop new mass spectrometry-based methods to understand the chemistry of microbes, our microbiome, and their ecological niche. In short, we develop tools that translate the chemical language between cells. This research requires the understanding of (microbial) genomics, proteomics, imaging mass spectrometry, genome mining, enzymology, small molecules structure elucidation, bioactivity screening, antibiotic resistance, and an understanding of small molecule structure elucidation methods. The collaborative mass spectrometry innovation center that he directs is well equipped and now has twelve mass spectrometers, that are used in the studies to investigate capture cellular chatter (e.g. metabolic exchange), metabolomics, metabolism and to develop methods to characterize natural products. These tools are used to define the spatial distribution of natural products in 2D, 3D, and in some cases real-time.

Areas of recent research directions are capturing mass spectrometry knowledge to understand the microbiome, non-invasive drug metabolism monitoring, informatics of metabolomics, microbe-microbe, microbe-immune cells, microbe-host, stem cell-cancer cell interactions, and diseased vs. non-disease model organisms, and the development of strategies for mass spectrometry-based genome mining and to detect and structurally characterize metabolites through crowdsource annotation of molecular information on the Global Natural Products Social Molecular Networking at http://gnps.ucsd.edu through the NIH supported center for computational mass spectrometry that is co-developed with Nuno Bandeira.

Kelly Hines, University of Georgia, Athens, Georgia, U.S.A.

Title: Isomeric lipid separations to assess membrane fluidity in antibiotic-resistant bacteria

Kelly Hines is an Assistant Professor in the Department of Chemistry at the University of Georgia. She has been recognized as a Female Role Model in Analytical Chemistry by Analytical and Bioanalytical Chemistry and as one of JASMS’s 2021 Outstanding Emerging Investigators. The Hines Lab is developing high-throughput and multidimensional IM-MS methods to study human health concerns at the molecular level, with an emphasis on antibiotic resistance and the role of lipids in host-pathogen interactions.

 

Xue Zhao, Tsinghua University, Beijing, China

Title: High throughput enzymatic assay for determining sn- selectivity of lysophosphatidylcholine acyltransferase

Xue Zhao is a Ph.D student at Tsinghua University in Beijing China. She developed a novel gas phase radical-directed dissociation (RDD) method based on mass spectrometry during her PhD research. This technique provides a powerful tool for detailed structural analysis of lipids and the lipidomic workflow for biological sample has been established. She has published three papers on Chem. Sci., 2019,10, 10740, Anal. Chem., 2020, 92, 14775, and J. Am. Soc. Mass. Spectrom., 2021, 32, 2, 560. She has received one Chinese patent. She participated in several academic conferences in China and received poster and oral awards. Currently, her RDD technique was applied to lipid biomarker discovery and bio-imaging.

Recordings (please log in to access)