Publications
Future perspectives in mass spectrometry of plant lipids
Abstract Plant lipid research has seen a tremendous progress in the last decades, particularly in the area of lipid analytics by mass spectrometry. This includes
01.04.2026
New Analytical Technologies to Resolve, Interpret, and Understand Lipid Complexity
Abstract The rapid and continued development of mass spectrometry–based technologies has significantly increased the capability to study and characterize lipids while providing new insight into
27.02.2026
Best practices and tools in R and Python for statistical processing and visualization of lipidomics and metabolomics data
Abstract Mass spectrometry-based lipidomics and metabolomics generate extensive data sets that, along with metadata such as clinical parameters, require specific data exploration skills to identify
09.10.2025
Quantitative Lipid Analysis of Extracellular Vesicle Preparations: A Perspective
ABSTRACT Quantitative lipidomic analysis performed by mass spectrometry is required for determination of the lipid content of extracellular vesicles (EVs). Such methods can provide information
17.03.2025
Checking out the Boundaries: Milestone in Lipidomics Achieved
Ring trial enables establishment of ceramide reference values Espoo, Finland – [Oct. 3rd, 2024] – Results of the first phase of a Ceramide Ring Trial
04.10.2024
Pitfalls in Lipid Mass Spectrometry of Mammalian Samples: A Brief Guide for Biologists
Oslo, Norway – [July 2nd 2024] – A collaborative team of leading scientists has published a crucial guide addressing the common pitfalls in lipid mass spectrometry
03.07.2024
- Gutbrod K, Dörmann P. Planta. Future perspectives in mass spectrometry of plant lipids. 2026 Mar 24;263(5):113.
- Ahrends R, Baker ES, Ekroos K, Ellis SR.Annu Rev Anal Chem (Palo Alto Calif). New Analytical Technologies to Resolve, Interpret, and Understand Lipid Complexity. 2026 Feb 24.
- Idkowiak J, Dehairs J, Schwarzerová J, Olešová D, Truong JXM, Kvasnička A, Eftychiou M, Cools R, Spotbeen X, Jirásko R, Veseli V, Giampà M, de Laat V, Butler LM, Weckwerth W, Friedecký D, Demeulemeester J, Hron K, Swinnen JV, Holčapek M. Best practices and tools in R and Python for statistical processing and visualization of lipidomics and metabolomics data. Nat Commun. 2025 Sep 30;16(1):8714.
- Hoffmann N, Ahrends R, Baker ES Ekroos K, Han X, Holčapek M, Liebisch G, Wenk MR, Xia Y, Köfeler HC. Introduction of a lipidomics scoring system for data quality assessment. J Lipid Res. 2025 Aug;66(8):100817.
- Schebb NH, Kampschulte N, Hagn G, Plitzko K, Meckelmann SW, Ghosh S, Joshi R, Kuligowski J, Vuckovic D, Botana MT, Sánchez-Illana Á, Zandkarimi F, Das A, Yang J, Schmidt L, Checa A, Roche HM, Armando AM, Edin ML, Lih FB, Aristizabal-Henao JJ, Miyamoto S, Giuffrida F, Moussaieff A, Domingues R, Rothe M, Hinz C, Das US, Rund KM, Taha AY, Hofstetter RK, Werner M, Werz O, Kahnt AS, Bertrand-Michel J, Le Faouder P, Gurke R, Thomas D, Torta F, Milic I, Dias IHK, Spickett CM, Biagini D, Lomonaco T, Idborg H, Liu JY, Fedorova M, Ford DA, Barden A, Mori TA, Kennedy PD, Maxey K, Ivanisevic J, Gallart-Ayala H, Gladine C, Wenk M, Galano JM, Durand T, Stark KD, Barbas C, Garscha U, Gelhaus SL, Ceglarek U, Flamand N, Griffin JL, Ahrends R, Arita M, Zeldin DC, Schopfer FJ, Quehenberger O, Julian R, Nicolaou A, Blair IA, Murphy MP, Hammock BD, Freeman B, Liebisch G, Serhan CN, Köfeler HC, Jakobsson PJ, Steinhilber D, Gelb MH, Holčapek M, Andrew R, Giera M, FitzGerald GA, Murphy RC, Newman JW, Dennis EA, Ekroos K, Milne GL, Gijón MA, Vesper HW, Wheelock CE, O’Donnell VB. Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry. Sci Signal. 2025 May 20;18(887):eadw1245.
- Skotland T, Ekroos K, Llorente A, Sandvig K.J Extracell Vesicles. Quantitative Lipid Analysis of Extracellular Vesicle Preparations: A Perspective. 2025 Mar;14(3):e70049
- Torta F, Hoffmann N, Burla B, Alecu I, Arita M, Bamba T, Bennett SAL, Bertrand-Michel J, Brügger B, Cala MP, Camacho-Muñoz D, Checa A, Chen M, Chocholoušková M, Cinel M, Chu-Van E, Colsch B, Coman C, Connell L, Sousa BC, Dickens AM, Fedorova M, Eiríksson FF, Gallart-Ayala H, Ghorasaini M, Giera M, Guan XL, Haid M, Hankemeier T, Harms A, Höring M, Holčapek M, Hornemann T, Hu C, Hülsmeier AJ, Huynh K, Jones CM, Ivanisevic J, Izumi Y, Köfeler HC, Lam SM, Lange M, Lee JC, Liebisch G, Lippa K, Lopez-Clavijo AF, Manzi M, Martinefski MR, Math RGH, Mayor S, Meikle PJ, Monge ME, Moon MH, Muralidharan S, Nicolaou A, Nguyen-Tran T, O’Donnell VB, Orešič M, Ramanathan A, Riols F, Saigusa D, Schock TB, Schwartz-Zimmermann H, Shui G, Singh M, Takahashi M, Thorsteinsdóttir M, Tomiyasu N, Tournadre A, Tsugawa H, Tyrrell VJ, van der Gugten G, Wakelam MO, Wheelock CE, Wolrab D, Xu G, Xu T, Bowden JA, Ekroos K, Ahrends R, Wenk MR. Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards. Nat Commun. 2024 Oct 3;15(1):8562.
- Skotland T, Ekroos K, McDonald J, Ahrends R, Liebisch G, Sandvig K. Pitfalls in lipid mass spectrometry of mammalian samples – a brief guide for biologists. Nat Rev Mol Cell Biol. 2024 Oct;25(10):759-760.
- Kopczynski D, Ejsing CS, McDonald JG, Bamba T, Baker ES, Bertrand-Michel J, Brügger B, Coman C, Ellis SR, Garrett TJ, Griffiths WJ, Guan XL, Han X, Höring M, Holčapek M, Hoffmann N, Huynh K, Lehmann R, Jones JW, Kaddurah-Daouk R, Köfeler HC, Meikle PJ, Metz TO, O’Donnell VB, Saigusa D, Schwudke D, Shevchenko A, Torta F, Vizcaíno JA, Welti R, Wenk MR, Wolrab D, Xia Y, Ekroos K, Ahrends R, Liebisch G. The lipidomics reporting checklist a framework for transparency of lipidomic experiments and repurposing resource data. J Lipid Res. 2024 Sep;65(9):100621.
- McDonald JG, Ejsing CS, Kopczynski D, Holčapek M, Aoki J, Arita M, Arita M, Baker ES, Bertrand-Michel J, Bowden JA, Brügger B, Ellis SR, Fedorova M, Griffiths WJ, Han X, Hartler J, Hoffmann N, Koelmel JP, Köfeler HC, Mitchell TW, O’Donnell VB, Saigusa D, Schwudke D, Shevchenko A, Ulmer CZ, Wenk MR, Witting M, Wolrab D, Xia Y, Ahrends R, Liebisch G, Ekroos K. Introducing the Lipidomics Minimal Reporting Checklist. Nat Metab. 2022 Sep;4(9):1086-1088.
- Köfeler HC, Eichmann TO, Ahrends R, Bowden JA, Danne-Rasche N, Dennis EA, Fedorova M, Griffiths WJ, Han X, Hartler J, Holčapek M, Jirásko R, Koelmel JP, Ejsing CS, Liebisch G, Ni Z, O’Donnell VB, Quehenberger O, Schwudke D, Shevchenko A, Wakelam MJO, Wenk MR, Wolrab D, Ekroos K. Quality control requirements for the correct annotation of lipidomics data. Nat Commun. 2021 Aug 6;12(1):4771.
- Köfeler HC, Ahrends R, Baker ES, Ekroos K, Han X, Hoffmann N, Holčapek M, Wenk MR, Liebisch G. Recommendations for good practice in MS-based lipidomics. J Lipid Res. 2021;62:100138.
- Liebisch G, Ahrends R., Arita M., Arita M., Bowden JA, Ejsing CS, Griffiths WJ, Holčapek M., Köfeler HC, Mitchell TW, Wenk MR, Ekroos K. 2019. Lipidomics needs more standardization. Nat Metab 1: 745-747.
- Burla B, Arita M, Arita M, Bendt AK, Cazenave-Gassiot A, Dennis EA, Ekroos K, Han X, Ikeda K, Liebisch G, Lin MK, Loh TP, Meikle PJ, Orešič M, Quehenberger O, Shevchenko A, Torta F, Wakelam MJO, Wheelock CE, Wenk MR. MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines. J Lipid Res. 2018 Oct;59(10):2001-2017.
- Liebisch G, Ekroos K, Hermansson M, Ejsing CS. Reporting of lipidomics data should be standardized. Biochim Biophys Acta. 2017 Aug;1862(8):747-751.
- Liebisch G, Ejsing CS, Ekroos K.Identification and Annotation of Lipid Species in Metabolomics Studies Need Improvement. Clin Chem. 2015 Dec;61(12):1542-4.
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