Location: Lipidomics group of Michal Holčapek, University of Pardubice, Faculty of Chemical Technology, Department of Analytical Chemistry, Czech Republic

Duration: 12 months

Starting date: January 2023, possible extension

The postdocs will work within the framework of the grant project “Multidimensional
chromatography – mass spectrometry quantitative workflows in the detailed
characterization of human plasma lipidome” funded by the Czech Science Foundation.

Position 1
The postdoc will learn and use the whole lipidomic workflow, which includes sample
preparation of biological samples using our extraction protocols, measurements using
ultrahigh-performance liquid chromatography – mass spectrometry (UHPLC/MS) or
ultrahigh-performance supercritical fluid chromatography – mass spectrometry
(UHPSFC/MS), data processing using LipidQuant software, and statistical evaluation
of data using advanced multivariate data analysis tools (e.g., Simca, R-scripts).
Requirements for position 1
1/ Ph.D. degree in (bio)analytical chemistry or closely related fields.
2/ Theoretical knowledge and experimental skills in mass spectrometry, liquid
chromatography, and LC/MS.
3/ Passion for science, ambition to achieve difficult goals, reliability, and teamwork.

Position 2
The postdoc will be involved mainly in the bioinformatic and biostatistical workflow,
which will include advanced statistical evaluation of the data using various tools for
multivariate data analysis and visualization of results, and the use of metabolic
pathway tools for data interpretation. The postdoc should implement availablesoftwares into our data processing workflow or may be involved in the development of
new software tools.
Requirements for position 2
1/ Ph.D. degree in bioinformatics, statistics, (bio)analytical chemistry, or related fields.
2/ Knowledge of multivariate data analysis, at least basic programming skills,
preferably in Python or R, advanced work with Excel.
3/ Passion for science, ambition to achieve difficult goals, reliability, and

More information: https://holcapek.upce.cz/

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