Best practices and tools in R and Python for statistical processing and visualization of lipidomics and metabolomics data
Abstract Mass spectrometry-based lipidomics and metabolomics generate extensive data sets that, along with metadata such as clinical parameters, require specific data exploration skills to identify and visualize statistically significant trends and biologically relevant differences. Besides tailored methods developed by individual labs, a solid core of freely accessible tools exists for exploratory data analysis and visualization, […]
Quantitative Lipid Analysis of Extracellular Vesicle Preparations: A Perspective
ABSTRACT Quantitative lipidomic analysis performed by mass spectrometry is required for determination of the lipid content of extracellular vesicles (EVs). Such methods can provide information about the total amount of lipids, the lipid species composition, the purityof EV samples as well as the cellular origin of the EVs. There are, however, many pitfalls when performing […]
Checking out the Boundaries: Milestone in Lipidomics Achieved
Ring trial enables establishment of ceramide reference values Espoo, Finland – [Oct. 3rd, 2024] – Results of the first phase of a Ceramide Ring Trial have just been published in the renowned journal Nature Communications, representing a significant landmark in the field of lipidomics. This achievement, coordinated by researchers at the University of Vienna and scientific […]
Pitfalls in Lipid Mass Spectrometry of Mammalian Samples: A Brief Guide for Biologists
Oslo, Norway – [July 2nd 2024] – A collaborative team of leading scientists has published a crucial guide addressing the common pitfalls in lipid mass spectrometry analyses of mammalian samples. The paper, titled “Pitfalls in Lipid Mass Spectrometry of Mammalian Samples – A Brief Guide for Biologists,” aims to improve the accuracy of lipid data reported […]